2005

All real-world events relating to the universe that occurred in 2005.

April

 * April 18 – Jock Elliott died.
 * April 26 – Family Guy: Stewie's Guide to World Domination was first published.

May

 * May 1 – aired for the first time.
 * The fourth season of started.


 * May 8 – aired for the first time.
 * May 13 – Ava Acres was born.
 * May 15 – aired for the first time.

June

 * June 5 – aired for the first time.
 * June 9 – Jon Clarke died.
 * June 12 – aired for the first time.
 * June 19 – aired for the first time.
 * June 26 – aired for the first time.

July

 * July 10 – aired for the first time.
 * July 12 – Issac Ryan Brown was born.
 * July 17 – aired for the first time.
 * July 24 – aired for the first time.

September

 * September 11 – aired for the first time.
 * September 18 – aired for the first time.
 * September 25 – aired for the first time.
 * September 27 – Stewie Griffin: The Untold Story was released direct-to-DVD.

November

 * November 1 – Family Guy: The Official Episode Guide: Seasons 1–3 was first published.
 * November 6 – aired for the first time.
 * November 13 – aired for the first time.
 * November 20 – aired for the first time.
 * November 27 – aired for the first time.

December

 * December 18 – aired for the first time.